After 3 years of exciting cooperative research the project EURO-Laminopathies - funded by the Commission of the European Communities - expires and the website will shortly convert to a communication platform of the EURO-Laminopathies team for future projects.
Laminopathies comprise a group of inherited diseases with variable clinical phenotypes. They are caused by mutations in the lamin complexes (LMNA) of the nuclear envelope. Prominent features of these human disorders are muscular dystrophy, cardiomyopathy, lipodystrophy, and progeria. Most of these diseases have postnatal onset, progressively developed during childhood or adolescence. Without treatment some laminopathies may lead to early death.
The EURO-Laminopathies team aims at
- understanding the basic functions and molecular mechanisms of lamin complexes relevant for the different types of laminopathies,
- increasing the patients' quality of life and
- attracting the attention of health professionals' for these rare diseases.