 |
Harald Herrmann, PhDGroup leader of B065 “Functional Architecture of the Cell”, Department of Molecular Genetics and Senior lecturer at the University of Heidelberg in Cell Biology Research
|
The group of Harald Herrmann contributes his knowledge and experience about the structure and assembly of intermediate filament proteins and of cytoplasmic crossbridging factors such as plectin and microtubule-associated proteins (MAPs). In particular, the mesenchymal protein vimentin as well as the muscle-specific protein desmin including disease-causing mutants forms of the latter protein were in the center of interest. Moreover, nuclear lamins from various sources have been recombinantly synthesized in order to investigate their structure and assembly properties. Using GFP-tagged versions, the importance of lamin mutations is followed by life cell imaging.
Working Group
Monika Zwerger, Dipl. Biol.
Address
Department Molecular Genetics,
German Cancer Research Center (DKFZ)
Im Neuenheimer Feld 580
69120 Heidelberg, Germany
Phone +49 6221 423 512
Fax +49 6221 423 519
